SCHEMBL1411615

SCHEMBL1411615

Br[C]1CCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22715250 0.95
SCHEMBL1411697 0.84
SCHEMBL11720183 0.80
SCHEMBL11326433 0.80
SCHEMBL6416270 0.74
SCHEMBL2221444 0.74
SCHEMBL2340201 0.65
SCHEMBL4923961 0.63
SCHEMBL16860542 0.60 TRIM24 (0.38)
SCHEMBL18112474 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024138286-A1 IL-17A MODULATORS USYNOVA PHARMACEUTICALS, LTD. (CN) 2024-07-04 WO disclosed
WO-2024139171-A1 IL-17A MODULATORS USYNOVA PHARMACEUTICALS, LTD. (CN) 2024-07-04 WO disclosed
US-11066422-B2 Method of producing cycloalkyl(trifluoromethyl)benzene TORAY FINE CHEMICALS CO., LTD. (JP) 2021-07-20 US disclosed
CN-112805001-A Inhibition of alpha v beta 6 integrins 莫菲克医疗股份有限公司 2021-05-14 CN disclosed
US-20210053992-A1 METHOD OF PRODUCING CYCLOALKYL(TRIFLUOROMETHYL)BENZENE TORAY FINE CHEMICALS CO., LTD. (JP) 2021-02-25 US disclosed
EP-3653594-A1 PRODUCTION METHOD FOR CYCLOALKYL(TRIFLUOROMETHYL)BENZENE Toray Fine Chemicals Co., Ltd. (JP) 2020-05-20 EP disclosed
CN-110062761-A Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and their use as GLUN2B receptor modulators 詹森药业有限公司 2019-07-26 CN disclosed
CN-108929336-A Thiazolopyrimidinone class as the active regulator of nmda receptor 豪夫迈·罗氏有限公司 2018-12-04 CN disclosed
CN-105764885-B The production method of acid and free-radical generating agent and acid and free radical 富士胶片和光纯药株式会社 2018-11-09 CN disclosed
CN-105612162-B Thiazolopyrimidinones as modulators of NMDA receptor activity 豪夫迈·罗氏有限公司 2018-08-21 CN disclosed
US-4069224-A N-(PYRIDYLALKYL)BENZAMIDES, IMPROVE PRODUCTION OF PROSTAGLANDINS IN MAMMALS THE UPJOHN COMPANY (US) 1978-01-17 US disclosed
US-RE29488-E CYCLOPENTADIENYL MANGANESE TRICARBONYL, CARBOXYMETHOXY-SUCCINIC ACIDS ETHYL CORPORATION (US) 1977-12-06 US disclosed
US-4059615-A INSECTICIDE, POLYMER INTERMEDIATE HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-11-22 US disclosed
US-4052171-A FUEL COMPOSITIONS AND ADDITIVE MIXTURES CONTAINING METHANETRICARBOXYLATES FOR REDUCING EXHAUST GAS CATALYST PLUGGING ETHYL CORPORATION (US) 1977-10-04 US disclosed
US-4008326-A INCREASING PRODUCTION OF PROSTAGLANDINS THE UPJOHN COMPANY (US) 1977-02-15 US disclosed
US-4005992-A CYCLOPENTADIENYL MAGNESIUM TRICARBONYL, OXYMETHYLENEMALONIC ACIDS OR ESTERS ETHYL CORPORATION (US) 1977-02-01 US disclosed
US-4005993-A CYCLOPENTADIENYL MANGANESE TRICARBONYL, OXYALKYL-MALONIC ACIDS OR ESTERS ETHYL CORPORATION (US) 1977-02-01 US disclosed
US-4001256-A PROSTAGLANDIN PRODUCTION IN MAMMALS THE UPJOHN COMPANY (US) 1977-01-04 US disclosed
US-3958955-A CYCLOPENTADIENYL MANGANESE TRICARBONYL ANTIKNOCK ETHYL CORPORATION (US) 1976-05-25 US disclosed
US-3950145-A ANTIKNOCK ETHYL CORPORATION (US) 1976-04-13 US disclosed