Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 12/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442367 | 0.77 | SQOR (0.74) | SQORALDH1A1GAAMAPK1ADORA2A | |
| SCHEMBL22208281 | 0.77 | SQOR (0.74) | SQORALDH1A1GAAMAPK1ADORA2A | |
| SCHEMBL22208214 | 0.71 | ADORA2A (0.59) | SQORADORA2AMAPT | |
| SCHEMBL29442335 | 0.71 | ADORA2A (0.59) | SQORADORA2AMAPT | |
| SCHEMBL22215937 | 0.69 | SQOR (0.73) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL29442372 | 0.68 | SQOR (0.83) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL29442282 | 0.64 | SQOR (1.00) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL22208387 | 0.64 | SQOR (1.00) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL29442346 | 0.63 | SQOR (0.83) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL22208330 | 0.62 | SQOR (0.67) | SQORALDH1A1GAAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146636-A1 | COMPOUNDS AND METHODS FOR TREATING OR PREVENTING HEART FAILURE | DREXEL UNIVERSITY (US) | 2020-07-16 | — | — | WO | disclosed |