Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 12/20 | 0.49 |
| ▸ | F10 | P00742 | 8/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221634 | 0.88 | CXCR3 (0.52) | CXCR3 | |
| SCHEMBL2265449 | 0.88 | CXCR3 (0.50) | CXCR3F10 | |
| SCHEMBL2270050 | 0.88 | CXCR3 (0.52) | CXCR3F10 | |
| SCHEMBL2277700 | 0.87 | CXCR3 (0.51) | CXCR3F10 | |
| SCHEMBL2271260 | 0.87 | CXCR3 (0.48) | CXCR3F10 | |
| SCHEMBL2276600 | 0.87 | CXCR3 (0.49) | CXCR3 | |
| SCHEMBL2354024 | 0.86 | CXCR3 (0.48) | CXCR3F10 | |
| SCHEMBL2223102 | 0.86 | CXCR3 (0.50) | CXCR3F10 | |
| SCHEMBL2272031 | 0.85 | CXCR3 (0.49) | CXCR3F10 | |
| SCHEMBL2265587 | 0.85 | CXCR3 (0.49) | CXCR3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084985-A1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-14 | — | — | WO | disclosed |