SCHEMBL2221630

SCHEMBL2221630

C1=CC1.O=S(=O)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.57
PKM P14618 1/20 0.57
LMNA P02545 2/20 0.54
CA2 P00918 5/20 0.52
CA12 O43570 2/20 0.52
CA9 Q16790 2/20 0.52
CA1 P00915 1/20 0.52
ENPP2 Q13822 1/20 0.52
ELANE P08246 1/20 0.48
RAPGEF4 Q8WZA2 1/20 0.48
CYP3A4 P08684 2/20 0.44
HTR6 P50406 2/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPK1 P28482 1/20 0.44
MPO P05164 1/20 0.44
CYP2C9 P11712 1/20 0.44
TSHR P16473 1/20 0.44
CA7 P43166 1/20 0.42
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29724901 0.89 GAA (0.67) GAAPKMLMNACA2CA12
SCHEMBL3792342 0.89 GAA (0.67) GAAPKMLMNACA2CA12
SCHEMBL18838 0.89 GAA (0.67) GAAPKMLMNACA2CA12
SCHEMBL124022 0.89 GAA (0.67) GAAPKMLMNACA2CA12
Hydrochloric Acid SCHEMBL10624752 0.87 GAA (0.64) GAAPKMLMNACA2CA12
Water SCHEMBL6425932 0.87 GAA (0.64) GAAPKMLMNACA2CA12
Hydrochloric Acid SCHEMBL10624747 0.87 GAA (0.64) GAAPKMLMNACA2CA12
SCHEMBL7938040 0.87 GAA (0.64) GAAPKMLMNACA2CA12
SCHEMBL11699158 0.87 GAA (0.64) GAAPKMLMNACA2CA12
Potassium SCHEMBL11745543 0.87 GAA (0.64) GAAPKMLMNACA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6620227-B1 Coated front (CF) ink containing ink base, acidic color developer and solvent; letterpress or offset printing without discoloration or smudging THE STANDARD REGISTER COMPANY 2003-09-16 US claimed
US-5888283-A AQUEOUS DISPERSION THE STANDARD REGISTER COMPANY (US) 1999-03-30 US claimed
WO-1998019867-A1 HIGH SOLIDS DIRECT THERMAL INK COMPOSITION AND METHOD OF MAKING AND USING SAME THE STANDARD REGISTER COMPANY (US) 1998-05-14 WO claimed
EP-3719096-A1 CURABLE ORGANOPOLYSILOXANE RELEASE AGENT COMPOSITION FOR THERMAL PAPER, THERMAL PAPER, AND THERMAL RECORDING LABEL SHEET Dow Toray Co., Ltd. (JP) 2020-10-07 EP disclosed
US-10202341-B2 Compositions comprising a reactive monomer and with a urea or urethane functional group ISP INVESTMENTS LLC (US) 2019-02-12 US disclosed
US-20170129856-A1 COMPOSITIONS COMPRISING A REACTIVE MONOMER AND WITH A UREA OR URETHANE FUNCTIONAL GROUP ISP INVESTMENTS LLC (US) 2017-05-11 US disclosed
CN-103880717-A Preparation method of bis(3-allyl-4-hydroxy phenyl) sulfone and derivative thereof JIANGSU AOLUNDA HIGH TECH INDUSTRY CO LTD 2014-06-25 CN disclosed
CN-103880717-A Preparation method of bis(3-allyl-4-hydroxy phenyl) sulfone and derivative thereof JIANGSU AOLUNDA HIGH TECH INDUSTRY CO LTD 2014-06-25 CN disclosed
US-20130004667-A1 COMPOSITIONS COMPRISING A REACTIVE MONOMER AND WITH A UREA OR URETHANE FUNCTIONAL GROUP ISP INVESTMENTS INC. (DE) 2013-01-03 US disclosed
WO-2011085150-A1 REACTIVE MONOMER FOR COATING AND/OR REACTIVE COATING ISP INVESTMENTS INC. (US) 2011-07-14 WO disclosed
EP-1677990-B1 IMPROVEMENTS IN THERMAL PAPER ARJO WIGGINS LTD (GB) 2008-10-22 EP disclosed
WO-2005032838-A1 IMPROVEMENTS IN THERMAL PAPER ARJO WIGGINS LIMITED (GB) 2005-04-14 WO disclosed
EP-0987122-B1 THERMAL RECORDING MATERIAL ASAHI DENKA KOGYO KK (JP) 2004-08-04 EP disclosed
US-6620227-B1 Coated front (CF) ink containing ink base, acidic color developer and solvent; letterpress or offset printing without discoloration or smudging THE STANDARD REGISTER COMPANY 2003-09-16 US disclosed
US-6432875-B1 LOW MOLECULAR WEIGHT POLYESTER ASAHI DENKA KOGYO K.K. (JP) 2002-08-13 US disclosed
JP-2002079759-A THERMAL RECORDING MATERIAL NIPPON KAYAKU CO LTD 2002-03-19 JP disclosed
JP-2002079758-A THERMAL RECORDING MATERIAL NIPPON KAYAKU CO LTD 2002-03-19 JP disclosed
EP-0987122-A1 THERMAL RECORDING MATERIAL ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2000-03-22 EP disclosed
US-5888283-A AQUEOUS DISPERSION THE STANDARD REGISTER COMPANY (US) 1999-03-30 US disclosed
WO-1998019867-A1 HIGH SOLIDS DIRECT THERMAL INK COMPOSITION AND METHOD OF MAKING AND USING SAME THE STANDARD REGISTER COMPANY (US) 1998-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170129856-A1 COMPOSITIONS COMPRISING A REACTIVE MONOMER AND WITH A UREA OR URETHANE FUNCTIONAL GROUP UROD, UFM1, UMPS GAA 3142/4885PKM 2883/4885LMNA 3047/4885
US-10202341-B2 Compositions comprising a reactive monomer and with a urea or urethane functional group UROD, UFM1, UMPS GAA 3142/4885PKM 2883/4885LMNA 3047/4885
US-20130004667-A1 COMPOSITIONS COMPRISING A REACTIVE MONOMER AND WITH A UREA OR URETHANE FUNCTIONAL GROUP UROD, UFM1, UMPS GAA 3142/4885PKM 2883/4885LMNA 3047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.