SCHEMBL2221785

SCHEMBL2221785

C=C(C)C(=O)OCCCCCCOc1ccc(C=CC(=O)OC)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.60
POLB P06746 1/20 0.60
APEX1 P27695 1/20 0.60
HTT P42858 1/20 0.60
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
TYR P14679 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KDM4E B2RXH2 1/20 0.45
MAPT P10636 1/20 0.45
HDAC3 O15379 1/20 0.45
STAT3 P40763 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9952834 1.00 TDP1 (0.60) TDP1POLBAPEX1HTTCA12
SCHEMBL9952791 1.00 TDP1 (0.60) TDP1POLBAPEX1HTTCA12
SCHEMBL9952787 1.00 TDP1 (0.60) TDP1POLBAPEX1HTTCA12
SCHEMBL9952732 1.00 TDP1 (0.60) TDP1POLBAPEX1HTTCA12
SCHEMBL9952829 1.00 TDP1 (0.60) TDP1POLBAPEX1HTTCA12
SCHEMBL2221782 1.00 TDP1 (0.60) TDP1POLBAPEX1HTTCA12
SCHEMBL9952736 1.00 TDP1 (0.60) TDP1POLBAPEX1HTTCA12
SCHEMBL9951812 0.99 TDP1 (0.57) TDP1POLBAPEX1HTTCA12
SCHEMBL9951811 0.99 TDP1 (0.57) TDP1POLBAPEX1HTTCA12
SCHEMBL12517641 0.98 TDP1 (0.57) TDP1POLBAPEX1HTTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220105697-A1 PHOTO-ALIGNABLE OBJECT ROLIC AG (CH) 2022-04-07 US claimed
EP-3036094-B1 METHOD OF PRODUCTION OF A PHOTO-ALIGNABLE OBJECT AND PHOTO-ALIGNABLE MATERIALS ROLIC TECH AG (CH) 2019-11-20 EP claimed
US-10465116-B2 Photoactive polymer materials ROLIC AG (CH) 2019-11-05 US claimed
US-10286616-B2 Photo-alignable object ROLIC AG (CH) 2019-05-14 US claimed
EP-3235852-A1 PHOTOACTIVE POLYMER MATERIALS Rolic AG (CH) 2017-10-25 EP claimed
EP-2655478-A1 PHOTOACTIVE POLYMER MATERIALS Rolic AG (CH) 2013-10-30 EP claimed
US-20130281564-A1 PHOTOACTIVE POLYMER MATERIALS ROLIC AG (CH) 2013-10-24 US claimed
WO-2012085048-A1 PHOTOACTIVE POLYMER MATERIALS ROLIC AG (CH) 2012-06-28 WO claimed
US-20260008878-A1 METHOD FOR THE PREPARATION OF PHOTOALIGNING POLYMER MATERIALS AND COMPOSITIONS Rolic Technologies AG (CH) 2026-01-08 US disclosed
US-12448473-B2 Method for the preparation of photoaligning polymer materials and compositions Rolic Technologies AG (CH) 2025-10-21 US disclosed
CN-115916853-B Polymer, and photo-alignment film and retardation film using the same 大阪有机化学工业株式会社 2024-07-09 CN disclosed
CN-110997614-B Method for preparing photoaligned polymeric materials and compositions 罗利克技术有限公司 2023-06-02 CN disclosed
CN-115916853-A Novel polymer, and photo-alignment film and retardation film using same 大阪有机化学工业株式会社 2023-04-04 CN disclosed
US-20220105697-A1 PHOTO-ALIGNABLE OBJECT ROLIC AG (CH) 2022-04-07 US disclosed
EP-1551898-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS Elsicon, Inc. (US) 2005-07-13 EP disclosed
US-6900271-B2 Hybrid polymer materials for liquid crystal alignment layers ELSICON, INC (US) 2005-05-31 US disclosed
US-20030232927-A1 Hybrid polymer materials for liquid crystal alignment layers ELSICON, INC. 2003-12-18 US disclosed
US-20030232930-A1 Hybrid polymer materials for liquid crystal alignment layers ELSICON, INC. 2003-12-18 US disclosed
WO-2003102046-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS ELSICON, INC. (US) 2003-12-11 WO disclosed
WO-2003102045-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS ELSICON, INC. (US) 2003-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008878-A1 METHOD FOR THE PREPARATION OF PHOTOALIGNING POLYMER MATERIALS AND COMPOSITIONS PYM1, SDC1, NAF1 TDP1 1333/4885POLB 977/4885APEX1 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.