SCHEMBL22218985

SCHEMBL22218985

c1ccc2c(c1)ccc1oc3ccc(-c4c5ccccc5c(-c5c6ccccc6c(-c6ccc7oc8ccc9ccccc9c8c7c6)c6ccccc56)c5ccccc45)cc3c12

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 6/20 0.45
AHR P35869 3/20 0.45
PAX8 Q06710 2/20 0.45
CYP1A1 P04798 1/20 0.45
CYP1A2 P05177 1/20 0.45
FYN P06241 1/20 0.45
MAPK3 P27361 1/20 0.45
TDP1 Q9NUW8 4/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HNF4A P41235 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10122694 0.98 ABCG2 (0.46) ABCG2AHRPAX8CYP1A1CYP1A2
SCHEMBL22217510 0.95 ABCG2 (0.49) ABCG2AHRPAX8CYP1A1CYP1A2
SCHEMBL22218984 0.95 KDM4E (0.44) ABCG2AHRPAX8CYP1A1CYP1A2
SCHEMBL22217512 0.95 ABCG2 (0.42) ABCG2AHRPAX8CYP1A1CYP1A2
SCHEMBL20127294 0.95 ABCG2 (0.44) ABCG2AHRPAX8CYP1A1CYP1A2
SCHEMBL20127292 0.94 TDP1 (0.44) ABCG2AHRPAX8CYP1A1CYP1A2
SCHEMBL20127306 0.94 KDM4E (0.45) ABCG2AHRPAX8CYP1A1CYP1A2
SCHEMBL10122503 0.94 ABCG2 (0.50) ABCG2AHRPAX8CYP1A1CYP1A2
SCHEMBL10122506 0.94 ABCG2 (0.43) ABCG2AHRPAX8CYP1A1CYP1A2
SCHEMBL22218986 0.93 ABCG2 (0.40) ABCG2AHRPAX8CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200227658-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200227658-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME PIEZO1, OCIAD1, SLCO4C1 ABCG2 2377/4885AHR 3647/4885PAX8 2423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.