Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22219850 | 0.91 | MAPT (0.54) | NR1H4KAT6AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24002288 | 0.88 | NR1H4 (0.53) | NR1H4KAT6AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22327061 | 0.86 | NR1H4 (0.58) | NR1H4KAT6AKMT2AALDH1A1MAPT | |
| SCHEMBL22327159 | 0.86 | MAPT (0.55) | NR1H4KAT6AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL26068727 | 0.84 | GAA (0.53) | NR1H4KAT6AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22598297 | 0.84 | MAPT (0.55) | NR1H4KAT6AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL26168185 | 0.82 | GAA (0.53) | KMT2ASMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL26068358 | 0.81 | GAA (0.48) | KMT2ASMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL26068352 | 0.81 | GAA (0.48) | KMT2ASMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL26068339 | 0.80 | GAA (0.48) | KMT2ASMN1; SMN2ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146397-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2020-07-16 | — | — | WO | disclosed |