Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22327399 | 0.91 | GAA (0.54) | GAAMAPTALDH1A1CHRM2MAOB | |
| SCHEMBL22219850 | 0.91 | MAPT (0.54) | GAAMAPTALDH1A1MAOBPOLB | |
| SCHEMBL26068727 | 0.86 | GAA (0.53) | GAAMAPTALDH1A1CHRM2MAOB | |
| SCHEMBL26068346 | 0.85 | GAA (0.48) | GAAMAPTALDH1A1CHRM2MAOB | |
| SCHEMBL26068339 | 0.85 | GAA (0.48) | GAAMAPTALDH1A1CHRM2MAOB | |
| SCHEMBL26068352 | 0.85 | GAA (0.48) | GAAMAPTALDH1A1CHRM2MAOB | |
| SCHEMBL26068358 | 0.85 | GAA (0.48) | GAAMAPTALDH1A1CHRM2MAOB | |
| SCHEMBL24023147 | 0.83 | GAA (0.55) | GAAMAPTALDH1A1MAOBPOLB | |
| SCHEMBL22219742 | 0.82 | NR1H4 (0.52) | GAAMAPTALDH1A1MAOBPOLB | |
| SCHEMBL22598297 | 0.82 | MAPT (0.55) | GAAMAPTALDH1A1MAOBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230160001-A1 | NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-05-25 | — | — | US | disclosed |