Sugi Predict

Sugi Predict / Compounds / SCHEMBL2222140

SCHEMBL2222140

SCHEMBL2222140

O=C(CCCc1ccccc1)OC(=O)CCCc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC1 Q13547 4/20 0.67
▸ HDAC3 O15379 3/20 0.67
▸ HDAC2 Q92769 3/20 0.67
▸ HDAC8 Q9BY41 3/20 0.67
▸ HDAC6 Q9UBN7 3/20 0.67
▸ HDAC5 Q9UQL6 3/20 0.67
▸ HDAC4 P56524 2/20 0.67
▸ HDAC7 Q8WUI4 2/20 0.67
▸ HDAC10 Q969S8 2/20 0.67
▸ HDAC11 Q96DB2 2/20 0.67
▸ HDAC9 Q9UKV0 2/20 0.67
▸ MAPK1 P28482 1/20 0.67
▸ ADRA1A P35348 1/20 0.67
▸ SLC6A3 Q01959 1/20 0.67
▸ SMN1; SMN2 Q16637 1/20 0.67
▸ TDP1 Q9NUW8 5/20 0.60
▸ NPC1 O15118 1/20 0.60
▸ CASP3 P42574 1/20 0.60
▸ RAB9A P51151 1/20 0.60
▸ SENP8 Q96LD8 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17223648 0.98 HDAC1 (0.64) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL7431738 0.96 TDP1 (0.63) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL13498527 0.96 MAPT (0.63) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL8790943 0.94 MAPT (0.66) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL7703558 0.93 HDAC1 (0.58) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL544942 0.93 HDAC1 (0.58) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL6423729 0.93 HDAC1 (0.58) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL10623470 0.92 MAPT (0.69) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL27603053 0.92 HDAC1 (0.62) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL11578613 0.92 MAPT (0.69) HDAC1HDAC3HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113956819-A Composite insulating adhesive film and preparation method and application thereof 深圳先进电子材料国际创新研究院 2022-01-21 — — CN claimed
CN-111806016-A Insulating adhesive film and preparation method thereof 中国科学院深圳先进技术研究院 2020-10-23 — — CN claimed
CN-110684477-A Composite structure insulating adhesive film and preparation method thereof 中国科学院深圳先进技术研究院 2020-01-14 — — CN claimed
CN-120025383-A Multi-target cisplatin complex, synthesis method and anticancer activity application thereof 河南师范大学 2025-05-23 — — CN disclosed
WO-2023137518-A1 PLATINUM COMPLEXES Western Sydney University (AU) 2023-07-27 — — WO disclosed
CN-111433964-B Electrolyte solution, electrochemical device, lithium ion secondary battery, and assembly 大金工业株式会社 2023-02-17 — — CN disclosed
US-20220251126-A1 ANTICANCER AGENTS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2022-08-11 — — US disclosed
EP-4010026-A1 ANTICANCER AGENTS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2022-06-15 — — EP disclosed
CN-110684477-B Composite structure insulating adhesive film and preparation method thereof 中国科学院深圳先进技术研究院 2021-09-07 — — CN disclosed
WO-2021024256-A1 ANTICANCER AGENTS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2021-02-11 — — WO disclosed
CN-111806016-A Insulating adhesive film and preparation method thereof 中国科学院深圳先进技术研究院 2020-10-23 — — CN disclosed
US-20110178199-A1 METHOD FOR PRODUCING ORGANIC COMPOUND AND ORGANIC COMPOUND OBTAINED BY THE METHOD M. TECHNIQUE CO., LTD. (JP) 2011-07-21 — — US disclosed
EP-2216312-A1 PROCESS FOR PRODUCING ORGANIC COMPOUND AND ORGANIC COMPOUND OBTAINED BY THE SAME M Technique Co., Ltd. (JP) 2010-08-11 — — EP disclosed
EP-0672648-B1 Threo (2R,3S)-3-amino-2-hydroxypentanoic acid and threo (2R,3S)-3-(p-methoxy-benzyloxycarbonyl/FMOC) amino-2-hydroxy-pentanoic acid ZAIDAN HOJIN BISEIBUTSU (JP) 1998-09-23 — — EP disclosed
EP-0672648-A1 Threo-3-amino-2-hydroxypentanoic acid and threo (2R,3S), (2S,3R)-3-(p-methoxy-benzyloxycarbonyl) amino-2-hydroxy-pentanoic acid ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1995-09-20 — — EP disclosed
US-5359138-A Endopeptidase inhibitors for treatment of amnesia and autoimmune diseases ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1994-10-25 — — US disclosed
US-5162500-A POSTSTATIN AND RELATED COMPOUNDS OR SALTS THEREOF ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1992-11-10 — — US disclosed
EP-0423358-A1 POSTOSTATIN AND RELATED COMPOUND THEREOF, OR THEIR SALTS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1991-04-24 — — EP disclosed
US-4006009-A 1-Thiadiazolyl-6-acyloxytetrahydropyrimidinone herbicides VELSICOL CHEMICAL CORPORATION (US) 1977-02-01 — — US disclosed
US-4004912-A 1-Thiadiazolyl-6-acyloxytetrahydropyrimidinone herbicides VELSICOL CHEMICAL CORPORATION (US) 1977-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220251126-A1 ANTICANCER AGENTS TP53, TOP2A, MKI67 HDAC1 295/4885HDAC3 923/4885HDAC2 1009/4885
US-20110178199-A1 METHOD FOR PRODUCING ORGANIC COMPOUND AND ORGANIC COMPOUND OBTAINED BY THE METHOD OR10J3, PORCN, ABCG2 HDAC1 4871/4885HDAC3 4855/4885HDAC2 4805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.