SCHEMBL2222208

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2223000	0.91	MAPT (0.51)	HSD11B1MAPTLMNAKDM4EPOLB
	SCHEMBL2224007	0.87	MAPT (0.55)	HSD11B1MAPTLMNAKDM4EPOLB
	SCHEMBL2353100	0.86	MAPT (0.59)	HSD11B1MAPTLMNAKDM4EPOLB
	SCHEMBL2221551	0.86	MAPT (0.66)	HSD11B1MAPTLMNAKDM4EPOLB
	SCHEMBL2225511	0.86	HSD11B1 (0.51)	HSD11B1MAPTLMNAKDM4EPOLB
	SCHEMBL2224197	0.85	MAPT (0.62)	HSD11B1MAPTLMNAKDM4EPOLB
	SCHEMBL2223697	0.84	MAPT (0.61)	HSD11B1MAPTLMNAKDM4EPOLB
	SCHEMBL2221714	0.84	MAPT (0.58)	HSD11B1MAPTLMNAKDM4EPOLB
	Hydrochloric Acid SCHEMBL2222038	0.83	MAPT (0.60)	HSD11B1MAPTLMNAKDM4EPOLB
	SCHEMBL2222116	0.83	MAPT (0.62)	HSD11B1MAPTLMNAKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.