Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 19/20 | 0.71 |
| ▸ | ITGB3 | P05106 | 18/20 | 0.71 |
| ▸ | ITGB6 | P18564 | 8/20 | 0.71 |
| ▸ | ITGB5 | P18084 | 7/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.71 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.65 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670827 | 0.94 | ITGAV (0.79) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL7172749 | 0.93 | ITGAV (0.77) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL7172733 | 0.93 | ITGAV (0.77) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6668568 | 0.91 | ITGAV (0.81) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL7170092 | 0.90 | ITGAV (0.79) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL7170078 | 0.90 | ITGAV (0.79) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL7204210 | 0.90 | ITGAV (0.74) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6671127 | 0.90 | ITGAV (0.73) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6670185 | 0.89 | ITGAV (0.75) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| Trifluoroacetic Acid SCHEMBL6671120 | 0.89 | ITGAV (0.79) | ITGAVITGB3ITGB6ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146521-A2 | RNAI AGENTS FOR INHIBITING EXPRESSION OF HIF-2 ALPHA (EPAS1), COMPOSITIONS THEREOF, AND METHODS OF USE | Arrowhead Pharmaceuticals, Inc. (US) | 2020-07-16 | — | — | WO | disclosed |