Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.68 |
| ▸ | ITGAV | P06756 | 20/20 | 0.68 |
| ▸ | ITGB5 | P18084 | 12/20 | 0.61 |
| ▸ | ITGB6 | P18564 | 11/20 | 0.58 |
| ▸ | ITGB8 | P26012 | 11/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30471830 | 0.87 | ITGB3 (0.67) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL15397316 | 0.87 | ITGB3 (0.79) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| Hydrochloric Acid SCHEMBL6425719 | 0.85 | ITGB3 (0.77) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL21329747 | 0.85 | ITGB3 (0.77) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL6422552 | 0.85 | ITGB3 (0.77) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| Hydrochloric Acid SCHEMBL6422102 | 0.85 | ITGB3 (0.77) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| Hydrochloric Acid SCHEMBL20487381 | 0.85 | ITGB3 (0.77) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| Hydrochloric Acid SCHEMBL6792186 | 0.84 | ITGB3 (0.76) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL5252527 | 0.83 | ITGB3 (0.73) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL6262063 | 0.83 | ITGB3 (0.74) | ITGB3ITGAVITGB5ITGB6ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146521-A2 | RNAI AGENTS FOR INHIBITING EXPRESSION OF HIF-2 ALPHA (EPAS1), COMPOSITIONS THEREOF, AND METHODS OF USE | Arrowhead Pharmaceuticals, Inc. (US) | 2020-07-16 | — | — | WO | disclosed |