SCHEMBL22223536

SCHEMBL22223536

c1ccc(-c2nc(-n3c4ccccc4c4c5ccc6ccc7ccccc7c6c5ccc43)nc3sc4ccccc4c23)cc1

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ RECQL P46063 1/20 0.32
▸ MMP14 P50281 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ ELANE P08246 1/20 0.31
▸ CYP1A1 P04798 1/20 0.30
▸ CYP1B1 Q16678 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23983434 0.89 ELANE (0.32) MEN1LMNAMAPTMAPK1RECQL
SCHEMBL22652359 0.88 ELANE (0.32) MEN1LMNAMAPTMAPK1RECQL
SCHEMBL23129066 0.87 ELANE (0.31) ELANE
SCHEMBL16905742 0.86 KDM4E (0.35) LMNAMAPTMAPK1KMT2ANPSR1
SCHEMBL22652454 0.86 ELANE (0.31) ELANE
SCHEMBL18961930 0.86 TNKS (0.30) —
SCHEMBL19246582 0.86 L3MBTL1 (0.38) MEN1MAPTMAPK1KMT2ANPSR1
SCHEMBL18961945 0.86 KDM4E (0.31) MAPTNPSR1ELANE
SCHEMBL22223548 0.85 MEN1 (0.35) MEN1LMNAMAPTMAPK1RECQL
SCHEMBL22211923 0.85 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11706981-B2 Organic light emitting device and compounds for use in same IDEMITSU KOSAN CO., LTD. (JP) 2023-07-18 — — US disclosed
US-11706981-B2 Organic light emitting device and compounds for use in same IDEMITSU KOSAN CO., LTD. (JP) 2023-07-18 — — US disclosed
US-20200227652-A1 ORGANIC LIGHT EMITTING DEVICE AND COMPOUNDS FOR USE IN SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11706981-B2 Organic light emitting device and compounds for use in same SLCO4C1, XPO6, ERCC1 MEN1 544/4885LMNA 1402/4885MAPT 485/4885
US-20200227652-A1 ORGANIC LIGHT EMITTING DEVICE AND COMPOUNDS FOR USE IN SAME SLCO4C1, XPO6, ERCC1 MEN1 544/4885LMNA 1402/4885MAPT 485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback