Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.70 |
| ▸ | PGR | P06401 | 7/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | IL5 | P05113 | 1/20 | 0.70 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.70 |
| ▸ | AR | P10275 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | MMP9 | P14780 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | THPO | P40225 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22224429 | 1.00 | NR3C1 (0.70) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL22224426 | 1.00 | NR3C1 (0.70) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL22224225 | 1.00 | NR3C1 (0.70) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL21152843 | 0.97 | NR3C1 (0.74) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL21152623 | 0.97 | NR3C1 (0.74) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL21153734 | 0.93 | NR3C1 (0.73) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL24591786 | 0.91 | NR3C1 (0.70) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL21153140 | 0.89 | NR3C1 (0.81) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL21152537 | 0.89 | NR3C1 (0.81) | NR3C1PGRCYP3A4HIF1ACYP2C9 | |
| SCHEMBL22224419 | 0.89 | NR3C1 (0.72) | NR3C1PGRCYP3A4HIF1ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146541-A2 | TRACELESS LINKERS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2020-07-16 | — | — | WO | disclosed |