SCHEMBL22224669

SCHEMBL22224669

O=P1(c2ccccc2)c2cccc3c2-c2c1cccc2P3(=O)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22225153 0.84 ALDH1A1 (0.42) —
SCHEMBL22224735 0.82 ALDH1A1 (0.43) —
SCHEMBL22225154 0.82 ALDH1A1 (0.36) —
SCHEMBL22225151 0.80 MEN1 (0.32) —
SCHEMBL12433902 0.80 MEN1 (0.33) HPGD
SCHEMBL21289377 0.79 ALDH1A1 (0.30) —
SCHEMBL18343556 0.78 MEN1 (0.36) HPGD
SCHEMBL22225165 0.78 KDM4E (0.50) HPGD
SCHEMBL12698474 0.78 ALDH1A1 (0.38) HPGD
SCHEMBL20026529 0.76 MAPT (0.31) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200227648-A1 COMPOUND AND ITS APPLICATION WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200227648-A1 COMPOUND AND ITS APPLICATION OCIAD1, OCIAD2, OSTC HPGD 904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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