Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.76 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.76 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.76 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 11/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22225674 | 0.91 | PIK3CD (0.74) | PIK3CDPIK3CAPIK3CBPIK3CGTSHR | |
| SCHEMBL22225682 | 0.87 | PIK3CG (0.69) | PIK3CDPIK3CAPIK3CBPIK3CGTSHR | |
| SCHEMBL1792641 | 0.86 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBPIK3CGMAPT | |
| SCHEMBL22225681 | 0.86 | PIK3CG (0.67) | PIK3CDPIK3CAPIK3CBPIK3CGTSHR | |
| SCHEMBL22225708 | 0.85 | PIK3CD (0.66) | PIK3CDPIK3CAPIK3CBPIK3CGTSHR | |
| SCHEMBL22225672 | 0.85 | PIK3CG (0.66) | PIK3CDPIK3CAPIK3CBPIK3CGTSHR | |
| SCHEMBL22225686 | 0.85 | PIK3CD (0.70) | PIK3CDPIK3CAPIK3CBPIK3CGTSHR | |
| SCHEMBL14053013 | 0.85 | PIK3CD (0.80) | PIK3CDPIK3CAPIK3CBPIK3CGTSHR | |
| SCHEMBL20644802 | 0.82 | PIK3CD (0.73) | PIK3CDPIK3CAPIK3CBPIK3CGMAPT | |
| SCHEMBL1790968 | 0.81 | PIK3CD (0.77) | PIK3CDPIK3CAPIK3CBPIK3CGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200223839-A1 | FLUORO-CONTAINING COMPOUNDS, USE AND PREPARATION THEREOF | JIANGSU YINGKEBEITA YIYAOKEJI CO LTD (CN) | 2020-07-16 | — | — | US | disclosed |
| CN-110958877-A | Fluorine-containing compound, use thereof and method for producing same | 江苏英科贝塔医药科技有限公司 | 2020-04-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200223839-A1 | FLUORO-CONTAINING COMPOUNDS, USE AND PREPARATION THEREOF | AFF1, AFF4, CYP2F1 | PIK3CD 1799/4885PIK3CA 729/4885PIK3CB 2056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.