Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16220464 | 1.00 | MAP3K12 (0.77) | MAP3K12 | |
| SCHEMBL16220395 | 0.89 | MAP3K12 (0.92) | MAP3K12 | |
| SCHEMBL15602409 | 0.87 | MAP3K12 (0.59) | MAP3K12 | |
| SCHEMBL16568693 | 0.87 | MAP3K12 (0.59) | MAP3K12 | |
| SCHEMBL16220036 | 0.87 | MAP3K12 (1.00) | MAP3K12 | |
| SCHEMBL16220063 | 0.87 | MAP3K12 (1.00) | MAP3K12 | |
| SCHEMBL16220384 | 0.87 | MAP3K12 (1.00) | MAP3K12 | |
| SCHEMBL16220406 | 0.85 | MAP3K12 (1.00) | MAP3K12 | |
| SCHEMBL16220089 | 0.85 | MAP3K12 (0.79) | MAP3K12 | |
| SCHEMBL17507038 | 0.85 | MAP3K12 (0.79) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991977-B1 | C-LINKED HETEROCYCLOALKYL SUBSTITUTED PYRIMIDINES AND THEIR USES | HOFFMANN LA ROCHE (CH) | 2020-07-22 | — | — | EP | claimed |
| EP-2991977-B1 | C-LINKED HETEROCYCLOALKYL SUBSTITUTED PYRIMIDINES AND THEIR USES | HOFFMANN LA ROCHE (CH) | 2020-07-22 | — | — | EP | disclosed |
| EP-2991977-B1 | C-LINKED HETEROCYCLOALKYL SUBSTITUTED PYRIMIDINES AND THEIR USES | HOFFMANN LA ROCHE (CH) | 2020-07-22 | — | — | EP | disclosed |