Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22227673 | 0.91 | ROCK2 (0.64) | ROCK2ROCK1 | |
| SCHEMBL22227667 | 0.87 | ROCK2 (0.65) | ROCK2ROCK1 | |
| SCHEMBL28489997 | 0.86 | ROCK2 (0.62) | ROCK2 | |
| SCHEMBL22227641 | 0.84 | ROCK2 (0.65) | ROCK2 | |
| SCHEMBL22227653 | 0.84 | ROCK2 (0.63) | ROCK2ROCK1 | |
| SCHEMBL28489710 | 0.83 | ROCK2 (0.62) | ROCK2 | |
| SCHEMBL28485273 | 0.80 | ROCK2 (0.64) | ROCK2ROCK1 | |
| SCHEMBL28477382 | 0.78 | ROCK2 (0.62) | ROCK2ROCK1 | |
| SCHEMBL19643211 | 0.78 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL17912941 | 0.78 | ROCK2 (0.64) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406426-B | Cyclic ureas as ROCK inhibitors | 百时美施贵宝公司 | 2020-11-20 | — | — | CN | claimed |
| EP-3242873-B1 | CYCLIC UREAS AS INHIBITORS OF ROCK | BRISTOL MYERS SQUIBB CO (US) | 2020-07-22 | — | — | EP | disclosed |