Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
| ▸ | PRKX | P51817 | 1/20 | 0.40 |
| ▸ | NEK2 | P51955 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12095465 | 0.91 | PDK2 (0.47) | CHEK1PRKD3MAP4K4RETMET | |
| SCHEMBL22228373 | 0.89 | CHEK1 (0.41) | CHEK1PRKD3MAP4K4RETMET | |
| SCHEMBL2893208 | 0.85 | CHEK1 (0.40) | CHEK1PRKD3MAP4K4RETMET | |
| SCHEMBL30569604 | 0.85 | CHEK1 (0.40) | CHEK1PRKD3MAP4K4RETMET | |
| SCHEMBL30543304 | 0.85 | CHEK1 (0.40) | CHEK1PRKD3MAP4K4RETMET | |
| SCHEMBL2776896 | 0.85 | CHEK1 (0.40) | CHEK1PRKD3MAP4K4RETMET | |
| SCHEMBL30569606 | 0.85 | CHEK1 (0.40) | CHEK1PRKD3MAP4K4RETMET | |
| SCHEMBL30656642 | 0.81 | PDK2 (0.45) | CHEK1PRKD3MAP4K4RETMET | |
| SCHEMBL12095513 | 0.81 | PDK2 (0.45) | CHEK1PRKD3MAP4K4RETMET | |
| SCHEMBL22294666 | 0.80 | PDK2 (0.44) | CHEK1PRKD3MAP4K4RETMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686185-B1 | FLUORENE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING HCV-RELATED DISEASE | SEOUL NAT UNIV R&DB FOUNDATION (KR) | 2023-12-13 | — | — | EP | disclosed |
| US-11261175-B2 | Fluorene derivative or pharmaceutically acceptable salt thereof, preparation method therefor, and pharmaceutical composition comprising same as effective ingredient for preventing or treating HCV-related disease | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2022-03-01 | — | — | US | disclosed |
| EP-3686185-A1 | FLUORENE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING HCV-RELATED DISEASE | Seoul National University R & DB Foundation (KR) | 2020-07-29 | — | — | EP | disclosed |
| US-20200231573-A1 | Fluorene Derivative or Pharmaceutically Acceptable Salt Thereof, Preparation Method Therefor, and Pharmaceutical Composition Comprising Same as Effective Ingredient for Preventing or Treating HCV-Related Disease | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11261175-B2 | Fluorene derivative or pharmaceutically acceptable salt thereof, preparation method therefor, and pharmaceutical composition comprising same as effective ingredient for preventing or treating HCV-related disease | SLC10A1, SLC39A11, FAR1 | CHEK1 4804/4885PRKD3 4354/4885MAP4K4 4459/4885 |
| US-20200231573-A1 | Fluorene Derivative or Pharmaceutically Acceptable Salt Thereof, Preparation Method Therefor, and Pharmaceutical Composition Comprising Same as Effective Ingredient for Preventing or Treating HCV-Related Disease | SLC10A1, SLC39A11, FAR1 | CHEK1 4804/4885PRKD3 4354/4885MAP4K4 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.