SCHEMBL2222920

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2225233	0.95	MAPT (0.56)	MAPTL3MBTL1NPSR1POLBKDM4E
	SCHEMBL2225657	0.94	MAPT (0.58)	MAPTL3MBTL1NPSR1POLBKDM4E
	SCHEMBL2221614	0.93	KDM4E (0.54)	MAPTL3MBTL1NPSR1POLBKDM4E
	SCHEMBL2223056	0.92	L3MBTL1 (0.58)	MAPTL3MBTL1NPSR1POLBKDM4E
	SCHEMBL12517082	0.92	MAPT (0.53)	MAPTL3MBTL1NPSR1POLBKDM4E
	SCHEMBL2221569	0.92	MAPT (0.54)	MAPTL3MBTL1NPSR1POLBKDM4E
	SCHEMBL2224521	0.90	MAPT (0.54)	MAPTL3MBTL1NPSR1POLBKDM4E
	SCHEMBL2221092	0.89	KDM4E (0.51)	MAPTL3MBTL1NPSR1POLBKDM4E
	SCHEMBL2221823	0.88	MAPT (0.53)	MAPTL3MBTL1NPSR1POLBKDM4E
	Hydrochloric Acid SCHEMBL2223177	0.87	MAPT (0.52)	MAPTL3MBTL1NPSR1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.