Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 8/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18215565 | 0.82 | MEN1 (0.44) | MEN1KMT2AGAAITGB2ICAM1 | |
| SCHEMBL17055976 | 0.80 | MEN1 (0.42) | MEN1KMT2AGAAITGB2ICAM1 | |
| SCHEMBL18371899 | 0.78 | GAA (0.42) | MEN1KMT2AGAAITGB2ICAM1 | |
| SCHEMBL6462215 | 0.77 | MEN1 (0.56) | MEN1KMT2AGAAITGB2ICAM1 | |
| SCHEMBL2575629 | 0.75 | CES2 (0.50) | GAAITGB2ICAM1ITGALHPGD | |
| SCHEMBL2575630 | 0.75 | CES2 (0.50) | GAAITGB2ICAM1ITGALHPGD | |
| SCHEMBL21466547 | 0.75 | GAA (0.39) | MEN1KMT2AGAAITGB2ICAM1 | |
| Methyl Alcohol SCHEMBL28365833 | 0.73 | GAA (0.53) | MEN1KMT2AGAAITGB2ICAM1 | |
| SCHEMBL695459 | 0.73 | GAA (0.56) | MEN1KMT2AGAAITGB2ICAM1 | |
| SCHEMBL29570977 | 0.73 | GAA (0.56) | MEN1KMT2AGAAITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088201-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-07-21 | — | — | WO | disclosed |