Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | USP7 | Q93009 | 2/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575435 | 0.77 | USP7 (0.41) | USP7RPS6KA3ESR1ESR2MEN1 | |
| SCHEMBL22230654 | 0.75 | POLB (0.41) | KDM4EALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL30082526 | 0.74 | ENPP3 (0.32) | ESR1ESR2ENPP1 | |
| SCHEMBL20447465 | 0.74 | ENPP3 (0.32) | ESR1ESR2ENPP1 | |
| SCHEMBL22230708 | 0.73 | USP7 (0.41) | USP7RPS6KA3ESR1ESR2MEN1 | |
| SCHEMBL19715634 | 0.69 | ENPP1 (0.41) | KDM4EENPP1 | |
| SCHEMBL29411821 | 0.69 | ENPP1 (0.41) | KDM4EENPP1 | |
| SCHEMBL30066802 | 0.67 | ENPP3 (0.33) | ENPP1 | |
| SCHEMBL3135646 | 0.67 | ALOX5AP (0.35) | USP7MEN1KMT2AALDH1A1POLB | |
| SCHEMBL9106225 | 0.66 | ENPP1 (0.39) | KDM4EENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020147739-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR | 武汉朗来科技发展有限公司 | 2020-07-23 | — | — | WO | disclosed |