Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29454055 | 1.00 | PLAU (0.37) | PLAULMNASCN9ASLC40A1POLB | |
| SCHEMBL29454154 | 0.81 | MEN1 (0.50) | MAPTKDM4EGAARAB9AMEN1 | |
| SCHEMBL22232308 | 0.81 | MEN1 (0.50) | MAPTKDM4EGAARAB9AMEN1 | |
| SCHEMBL29454077 | 0.80 | RAB9A (0.43) | LMNAALDH1A1MAPTKDM4EGAA | |
| SCHEMBL22232392 | 0.80 | RAB9A (0.43) | LMNAALDH1A1MAPTKDM4EGAA | |
| SCHEMBL31723212 | 0.80 | RAB9A (0.43) | LMNAALDH1A1MAPTKDM4EGAA | |
| SCHEMBL29454255 | 0.75 | LCK (0.38) | POLBALDH1A1MAPTKDM4EGAA | |
| SCHEMBL22231909 | 0.75 | LCK (0.38) | POLBALDH1A1MAPTKDM4EGAA | |
| SCHEMBL31723213 | 0.75 | DHODH (0.43) | LMNAPOLBALDH1A1KDM4ERAB9A | |
| SCHEMBL29454100 | 0.75 | DHODH (0.43) | LMNAPOLBALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911629-A1 | 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF | PI Industries Ltd. (IN) | 2021-11-24 | — | — | EP | claimed |
| WO-2020148617-A1 | 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-07-23 | — | — | WO | claimed |