Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.43 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 3/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10094685 | 0.92 | ABL1 (0.46) | ABL1AGPAT2NISCHPDE2APDE10A | |
| SCHEMBL16574077 | 0.89 | MAP4K4 (0.40) | ABL1AGPAT2PDE2APDE10ACHRM3 | |
| SCHEMBL8054650 | 0.81 | ABL1 (0.49) | ABL1AGPAT2NISCHPDE2APDE10A | |
| SCHEMBL16574089 | 0.81 | IDO1 (0.42) | ABL1AGPAT2PDE2APDE10ACHRM3 | |
| SCHEMBL22820237 | 0.81 | ABL1 (0.43) | ABL1NISCHPDE2APDE10A | |
| SCHEMBL10094663 | 0.80 | ESR2 (0.46) | ABL1AGPAT2PDE2APDE10ACHRM3 | |
| SCHEMBL5069743 | 0.77 | PDE2A (0.43) | ABL1AGPAT2NISCHPDE2APDE10A | |
| SCHEMBL23992671 | 0.76 | MAP4K4 (0.39) | ABL1AGPAT2PDE2APDE10ARAPGEF4 | |
| SCHEMBL12365161 | 0.76 | ABL1 (0.49) | ABL1AGPAT2CHRM3RAPGEF4PGR | |
| SCHEMBL18772851 | 0.76 | AGPAT2 (0.50) | ABL1AGPAT2NISCHPDE2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911629-A1 | 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF | PI Industries Ltd. (IN) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020148617-A1 | 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-07-23 | — | — | WO | disclosed |