Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16574089 | 0.91 | IDO1 (0.42) | MAP4K4IDO1L3MBTL1RAPGEF4CYP3A4 | |
| SCHEMBL16574077 | 0.87 | MAP4K4 (0.40) | MAP4K4IDO1L3MBTL1RAPGEF4CYP3A4 | |
| SCHEMBL16574096 | 0.87 | CYP3A4 (0.45) | MAP4K4IDO1RAPGEF4CYP3A4AGPAT2 | |
| SCHEMBL22820237 | 0.83 | ABL1 (0.43) | PDE2APDE10AABL1 | |
| SCHEMBL16574097 | 0.83 | IDO1 (0.42) | MAP4K4IDO1RAPGEF4CYP3A4AGPAT2 | |
| SCHEMBL16574081 | 0.80 | AGPAT2 (0.42) | MAP4K4IDO1L3MBTL1RAPGEF4CYP3A4 | |
| SCHEMBL16574156 | 0.79 | L3MBTL1 (0.48) | MAP4K4IDO1L3MBTL1CYP3A4AGPAT2 | |
| SCHEMBL16574087 | 0.79 | MEN1 (0.43) | MAP4K4IDO1L3MBTL1AGPAT2ABL1 | |
| SCHEMBL26465507 | 0.79 | GAA (0.44) | MAP4K4IDO1RAPGEF4CYP3A4AGPAT2 | |
| SCHEMBL16574104 | 0.78 | MAP4K4 (0.48) | MAP4K4IDO1L3MBTL1CYP3A4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338665-A1 | MEDICAL USE OF PROSTACYCLIN RECEPTOR AGONIST | CHINESE PLA GENERAL HOSPITAL (CN) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338665-A1 | MEDICAL USE OF PROSTACYCLIN RECEPTOR AGONIST | PTGIR, CYP11B2, PDE8A | MAP4K4 1341/4885IDO1 1573/4885L3MBTL1 4714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.