Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.39 |
| ▸ | ROR1 | Q01973 | 4/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | ABL2 | P42684 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichloroacetic Acid SCHEMBL22232737 | 0.95 | ABL1 (0.37) | ABL1ROR1FGFR1FGFR2FGFR4 | |
| SCHEMBL22232778 | 0.93 | ABL1 (0.39) | ABL1ROR1FGFR1FGFR2FGFR4 | |
| SCHEMBL22232763 | 0.91 | ABL1 (0.39) | ABL1ROR1FGFR1FGFR2FGFR4 | |
| SCHEMBL22232746 | 0.89 | CSF1R (0.41) | ABL1ROR1FGFR1FGFR2FGFR4 | |
| Trichloroacetic Acid SCHEMBL22232789 | 0.84 | CSF1R (0.38) | ABL1ROR1CSF1RRET | |
| SCHEMBL22232810 | 0.82 | ROR1 (0.37) | ABL1ROR1FGFR1FGFR2FGFR4 | |
| Trifluoroacetic Acid SCHEMBL22232764 | 0.81 | ABL1 (0.36) | ABL1ROR1FGFR1FGFR2FGFR4 | |
| SCHEMBL22232785 | 0.81 | NTRK3 (0.40) | ABL1FGFR3ABL2MAPK14 | |
| SCHEMBL22232739 | 0.80 | ABL1 (0.41) | ABL1ROR1FGFR1FGFR2FGFR4 | |
| SCHEMBL22232696 | 0.80 | ROR1 (0.49) | ABL1ROR1FGFR1FGFR2FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020149553-A1 | ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR TREATMENT OF KINASE-RELATED DISEASE | 주식회사 보로노이 | 2020-07-23 | — | — | WO | claimed |
| WO-2020149553-A1 | ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR TREATMENT OF KINASE-RELATED DISEASE | 주식회사 보로노이 | 2020-07-23 | — | — | WO | disclosed |