Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.41 |
| ▸ | ROR1 | Q01973 | 5/20 | 0.39 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | ABL2 | P42684 | 2/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.34 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL22232779 | 0.96 | ABL1 (0.42) | ABL1ROR1CSF1RFGFR1FGFR2 | |
| SCHEMBL22232696 | 0.90 | ROR1 (0.49) | ABL1ROR1CSF1RFGFR1FGFR2 | |
| Hydrochloric Acid SCHEMBL22232709 | 0.90 | ROR1 (0.48) | ABL1ROR1CSF1RFGFR1FGFR2 | |
| Trifluoroacetic Acid SCHEMBL22232725 | 0.88 | ABL1 (0.46) | ABL1ROR1CSF1RFGFR1FGFR2 | |
| SCHEMBL22232778 | 0.87 | ABL1 (0.39) | ABL1ROR1CSF1RFGFR1FGFR2 | |
| SCHEMBL22232810 | 0.86 | ROR1 (0.37) | ABL1ROR1CSF1RFGFR1FGFR2 | |
| SCHEMBL22232821 | 0.85 | ROR1 (0.37) | ABL1ROR1CSF1RFGFR1FGFR2 | |
| Trifluoroacetic Acid SCHEMBL22232764 | 0.85 | ABL1 (0.36) | ABL1ROR1CSF1RFGFR1FGFR2 | |
| Trifluoroacetic Acid SCHEMBL22232777 | 0.83 | ABL1 (0.35) | ABL1ROR1CSF1RFGFR1FGFR2 | |
| SCHEMBL22232702 | 0.80 | ABL1 (0.39) | ABL1ROR1CSF1RFGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020149553-A1 | ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR TREATMENT OF KINASE-RELATED DISEASE | 주식회사 보로노이 | 2020-07-23 | — | — | WO | disclosed |