Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 7/20 | 0.62 |
| ▸ | CLK1 | P49759 | 2/20 | 0.47 |
| ▸ | CLK2 | P49760 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.46 |
| ▸ | CHUK | O15111 | 4/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199020 | 1.00 | TTK (0.62) | TTKCLK1CLK2LRRK2CHUK | |
| SCHEMBL22234195 | 0.97 | TTK (0.65) | TTKCLK1CLK2LRRK2CHUK | |
| SCHEMBL22233302 | 0.97 | TTK (0.67) | TTKCLK1CLK2LRRK2CHUK | |
| SCHEMBL30199272 | 0.97 | TTK (0.67) | TTKCLK1CLK2LRRK2CHUK | |
| SCHEMBL30199108 | 0.97 | TTK (0.65) | TTKCLK1CLK2LRRK2CHUK | |
| SCHEMBL22232835 | 0.96 | TTK (0.68) | TTKCLK1CLK2LRRK2CHUK | |
| SCHEMBL30198875 | 0.96 | TTK (0.68) | TTKCLK1CLK2LRRK2CHUK | |
| SCHEMBL25107268 | 0.94 | TTK (0.65) | TTKCLK1CLK2LRRK2CHUK | |
| SCHEMBL30199146 | 0.94 | TTK (0.65) | TTKCLK1CLK2LRRK2CHUK | |
| SCHEMBL22234538 | 0.91 | TTK (0.59) | TTKCLK1CLK2LRRK2CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020149723-A1 | PYRROLOPYRIMIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING PROTEIN KINASE-RELATED DISEASE COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 보로노이 | 2020-07-23 | — | — | WO | claimed |
| US-20230066011-A1 | PYRROLOPYRIMIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING PROTEIN KINASE-RELATED DISEASE COMPRISING SAME AS ACTIVE INGREDIENT | VORONOIBIO CO., LTD. (KR) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230066011-A1 | PYRROLOPYRIMIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING PROTEIN KINASE-RELATED DISEASE COMPRISING SAME AS ACTIVE INGREDIENT | LRRK2, BRCA1, PARK7 | TTK 109/4885CLK1 266/4885CLK2 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.