SCHEMBL2223364

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2223250	0.92	CACNA1I (0.45)	CXCR3CACNA1HCACNA1IKCNH2CRHBP
	SCHEMBL2222817	0.92	CXCR3 (0.50)	CXCR3CACNA1IKCNH2ATMACKR3
	SCHEMBL2224894	0.91	IDH2 (0.46)	CXCR3ACKR3LMNASMN1; SMN2MAPT
	SCHEMBL2266970	0.90	CXCR3 (0.64)	CXCR3CACNA1HCACNA1IKCNH2LMNA
	SCHEMBL2221634	0.90	CXCR3 (0.52)	CXCR3CACNA1IKCNH2ATMLMNA
	SCHEMBL2222814	0.90	CXCR3 (0.52)	CXCR3CACNA1IKCNH2ATMLMNA
	SCHEMBL12516595	0.89	CXCR3 (0.55)	CXCR3CACNA1IKCNH2ATMLMNA
	SCHEMBL2270050	0.89	CXCR3 (0.52)	CXCR3CACNA1HCACNA1IKCNH2ATM
	SCHEMBL2272108	0.89	CXCR3 (0.42)	CXCR3CACNA1IATMACKR3MEN1
	SCHEMBL2224637	0.89	CXCR3 (0.51)	CXCR3CACNA1IKCNH2ATMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.