Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | RARG | P13631 | 3/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29498868 | 1.00 | RXRA (0.39) | RXRACYP3A4RXRGMAPK1RARB | |
| SCHEMBL7081365 | 0.80 | RXRA (0.49) | RXRACYP3A4RXRGMAPK1RARB | |
| SCHEMBL7081366 | 0.80 | RXRA (0.40) | RXRACYP3A4RXRGMAPK1RARB | |
| SCHEMBL22235311 | 0.78 | MAPK1 (0.45) | MAPK1MAPTHPGDKDM4EL3MBTL1 | |
| SCHEMBL29498842 | 0.78 | RXRA (0.38) | RXRACYP3A4RXRGMAPK1RARB | |
| SCHEMBL22235726 | 0.78 | RXRA (0.38) | RXRACYP3A4RXRGMAPK1RARB | |
| SCHEMBL22235642 | 0.76 | KDM4E (0.45) | MAPK1MAPTHPGDKDM4EL3MBTL1 | |
| SCHEMBL29498855 | 0.76 | KDM4E (0.45) | MAPK1MAPTHPGDKDM4EL3MBTL1 | |
| SCHEMBL22235635 | 0.75 | MAPK1 (0.48) | MAPK1MAPTHPGDKDM4EL3MBTL1 | |
| SCHEMBL29498889 | 0.75 | MAPK1 (0.48) | MAPK1MAPTHPGDKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911309-A1 | COMPOSITIONS AND METHODS FOR IMMUNE MODULATION AND TREATMENT OF CANCER | Board Of Trustees Of Michigan State University (US) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020150668-A1 | COMPOSITIONS AND METHODS FOR IMMUNE MODULATION AND TREATMENT OF CANCER | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2020-07-23 | — | — | WO | disclosed |