Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22235591 | 1.00 | EPHX1 (0.33) | EPHX1ESR1ESR2KDM1AEPHX2 | |
| SCHEMBL17624414 | 0.81 | HRH4 (0.36) | EPHX1ESR1ESR2JAK2JAK1 | |
| SCHEMBL18498060 | 0.81 | CHRNB2 (0.39) | — | |
| SCHEMBL18498063 | 0.81 | CHRNB2 (0.39) | — | |
| SCHEMBL19504677 | 0.78 | ATM (0.39) | EPHX1ESR1ESR2JAK2JAK1 | |
| SCHEMBL22248806 | 0.77 | CHRNA4 (0.55) | — | |
| SCHEMBL28672272 | 0.77 | CHRNA4 (0.55) | — | |
| SCHEMBL3290798 | 0.76 | PDK2 (0.36) | EPHX1ESR1ESR2KDM1A | |
| SCHEMBL13000721 | 0.75 | ESR1 (0.33) | EPHX1ESR1ESR2KDM1AJAK2 | |
| Hydrochloric Acid SCHEMBL22235812 | 0.75 | CHRNA4 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911643-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | Curza Global LLC (US) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |