SCHEMBL2223565

SCHEMBL2223565

CC(C)(CCc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 7/20 0.49
FFAR1 O14842 1/20 0.45
PPARG P37231 4/20 0.45
PPARD Q03181 3/20 0.45
ALDH1A1 P00352 2/20 0.45
PTGES2 Q9H7Z7 1/20 0.45
FABP2 P12104 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2C19 P33261 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
SLC13A5 Q86YT5 2/20 0.44
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22921420 0.90 SLC13A5 (0.50) PPARAPPARGSMN1; SMN2CYP1A2SLC13A5
SCHEMBL22728703 0.89 PPARA (0.54) PPARAFFAR1PPARGPPARDALDH1A1
SCHEMBL11569485 0.85 ALDH1A1 (0.44) FFAR1ALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL29314248 0.85 SLC13A5 (0.46) PPARACYP1A2SLC13A5
SCHEMBL25996884 0.83 SLC13A5 (0.45) PPARAALDH1A1CYP1A2SLC13A5
SCHEMBL15496714 0.83 PPARA (0.48) PPARAFFAR1PPARGPPARDSMN1; SMN2
SCHEMBL173883 0.82 CYP1A2 (0.51) PPARAFFAR1ALDH1A1SMN1; SMN2CYP1A2
SCHEMBL30080837 0.82 CYP1A2 (0.51) PPARAFFAR1ALDH1A1SMN1; SMN2CYP1A2
SCHEMBL9324204 0.82 PRMT1 (0.55) ALDH1A1MAPTTDP1
SCHEMBL24440172 0.81 GRM2 (0.50) FFAR1ALDH1A1SLC13A5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2604595-B1 TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY SHIONOGI & CO (JP) 2016-03-16 EP disclosed
EP-2604595-A1 TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY Shionogi&Co., Ltd. (JP) 2013-06-19 EP disclosed
WO-2011084846-A1 QUATERNARY AMMONIUM SALT PRODRUGS ALKERMES, INC. (US) 2011-07-14 WO disclosed