Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UMPS | P11172 | 2/20 | 0.54 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | EIF4E | P06730 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795431 | 1.00 | UMPS (0.54) | UMPSPNPSMN1; SMN2KDM4EALDH1A1 | |
| Pyrazofurin SCHEMBL21379808 | 0.86 | UMPS (0.61) | UMPSPNPSMN1; SMN2KDM4EALDH1A1 | |
| Pyrazofurin SCHEMBL28176565 | 0.85 | UMPS (0.60) | UMPSPNPSMN1; SMN2KDM4EALDH1A1 | |
| Pyrazofurin SCHEMBL28138546 | 0.84 | UMPS (0.58) | UMPSPNPSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9051201 | 0.83 | UMPS (0.51) | UMPSPNPSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4557441 | 0.80 | UMPS (0.52) | UMPSPNPSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL21539496 | 0.80 | UMPS (0.52) | UMPSPNPSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9053021 | 0.78 | UMPS (0.48) | UMPSPNPPYGL | |
| SCHEMBL22672223 | 0.71 | UMPS (0.55) | UMPSPYGL | |
| SCHEMBL7141012 | 0.71 | UMPS (0.55) | UMPSPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911332-A1 | EXPANDABLE MEMBER SYSTEMS AND METHODS FOR DRUG DELIVERY | Intersect ENT, Inc. (US) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020150607-A1 | EXPANDABLE MEMBER SYSTEMS AND METHODS FOR DRUG DELIVERY | INTERSECT ENT, INC. (US) | 2020-07-23 | — | — | WO | disclosed |