Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 6/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL763623 | 0.85 | MME (0.49) | ACACBMMEEPHX1KMT2AMEN1 | |
| SCHEMBL1699496 | 0.85 | MME (0.49) | ACACBMMEEPHX1KMT2AMEN1 | |
| SCHEMBL13643095 | 0.85 | MME (0.49) | ACACBMMEEPHX1KMT2AMEN1 | |
| SCHEMBL1697565 | 0.84 | EPHX1 (0.50) | ACACBMMEEPHX1KMT2AMEN1 | |
| SCHEMBL1696260 | 0.83 | ESR1 (0.53) | — | |
| SCHEMBL24591934 | 0.82 | MME (0.47) | ACACBMMEEPHX1KMT2AMEN1 | |
| SCHEMBL15134806 | 0.81 | NPC1 (0.43) | EPHX1NPC1RAB9AALDH1A1 | |
| SCHEMBL16691549 | 0.81 | ALPI (0.52) | NPC1RAB9AALDH1A1 | |
| SCHEMBL10835297 | 0.81 | ALPI (0.52) | NPC1RAB9AALDH1A1 | |
| SCHEMBL3654051 | 0.77 | L3MBTL1 (0.45) | ACACBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911643-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | Curza Global LLC (US) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |