Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CDK14 | O94921 | 3/20 | 0.43 |
| ▸ | CCNY | Q8ND76 | 3/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22236014 | 0.90 | CLK2 (0.52) | CLK2DYRK1A | |
| SCHEMBL22235966 | 0.89 | KCNQ3 (0.52) | SLC6A3KCNH2TAAR1TRPV1KCNQ3 | |
| SCHEMBL22258273 | 0.88 | KCNQ3 (0.51) | TRPV1KCNQ3KCNQ2 | |
| SCHEMBL22236223 | 0.87 | USP36 (0.50) | KCNQ3KCNQ2KCNE1KCNQ1CLK2 | |
| SCHEMBL22235792 | 0.87 | ABL1 (0.45) | KCNQ3KCNQ2KCNE1KCNQ1CLK2 | |
| SCHEMBL22236228 | 0.87 | CLK2 (0.41) | TRPV1KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL22236058 | 0.86 | USP36 (0.44) | SLC6A3KCNH2TAAR1KCNQ3KCNQ2 | |
| SCHEMBL22235863 | 0.85 | CLK2 (0.51) | SLC6A3KCNH2TAAR1KCNQ3KCNQ2 | |
| SCHEMBL22236062 | 0.85 | PTPN1 (0.42) | PTPN1KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL22236081 | 0.81 | CLK2 (0.68) | CLK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |