Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628157 | 0.87 | LTB4R2 (0.56) | HDAC1HDAC3HDAC2NCOR2LTB4R2 | |
| SCHEMBL20236489 | 0.86 | HDAC1 (0.48) | HDAC1HDAC3HDAC2NCOR2LTB4R2 | |
| SCHEMBL22236346 | 0.83 | HDAC1 (0.52) | HDAC1HDAC3HDAC2NCOR2LTB4R2 | |
| SCHEMBL20236425 | 0.82 | HDAC1 (0.56) | HDAC1HDAC3HDAC2NCOR2LTB4R2 | |
| SCHEMBL4315970 | 0.82 | PTGES (0.54) | HDAC1HDAC3HDAC2NCOR2LTB4R2 | |
| SCHEMBL18464032 | 0.81 | LTB4R2 (0.57) | HDAC1HDAC3HDAC2NCOR2LTB4R2 | |
| SCHEMBL22218294 | 0.81 | PTPRB (0.53) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL4332066 | 0.81 | HDAC1 (0.48) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL2484830 | 0.80 | HDAC1 (0.49) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL28218883 | 0.80 | HDAC1 (0.54) | HDAC1HDAC3HDAC2NCOR2LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10717716-B2 | 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2020-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717716-B2 | 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same | HDAC1, HDAC5, HDAC2 | HDAC1 1/4885HDAC3 5/4885HDAC2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.