Mupirocin

Mupirocin

SCHEMBL2223711

C/C(=C\C(=O)OCCCCCCCCC(=O)O)C[C@@H]1OC[C@H](C[C@@H]2O[C@H]2[C@@H](C)[C@H](C)O)[C@@H](O)[C@H]1O.C/C(=C\C(=O)OCCCCCCCCC(=O)O)C[C@@H]1OC[C@H](C[C@@H]2O[C@H]2[C@@H](C)[C@H](C)O)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ileS

The experimentally established mechanism targets of Mupirocin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IARS1 P41252 4/20 1.00
HTR2A P28223 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mupirocin SCHEMBL18995884 1.00 IARS1 (1.00) IARS1HTR2A
Mupirocin SCHEMBL14022405 1.00 IARS1 (1.00) IARS1HTR2A
Mupirocin SCHEMBL1027616 1.00 IARS1 (1.00) IARS1HTR2A
Mupirocin SCHEMBL3291 1.00 IARS1 (1.00) IARS1HTR2A
Mupirocin SCHEMBL15307512 1.00 IARS1 (1.00) IARS1HTR2A
Mupirocin SCHEMBL15387504 1.00 IARS1 (1.00) IARS1HTR2A
Mupirocin SCHEMBL18998277 1.00 IARS1 (1.00) IARS1HTR2A
Mupirocin SCHEMBL15387505 1.00 IARS1 (1.00) IARS1HTR2A
Mupirocin SCHEMBL19183296 1.00 IARS1 (1.00) IARS1HTR2A
Mupirocin SCHEMBL14616863 1.00 IARS1 (1.00) IARS1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3655104-A1 AN OSTEOADSORPTIVE FLUOROGENIC SUBSTRATE OF CATHEPSIN K FOR IMAGING OSTEOCLAST ACTIVITY AND MIGRATION The Regents of the University of California (US) 2020-05-27 EP disclosed
WO-2019018238-A1 AN OSTEOADSORPTIVE FLUOROGENIC SUBSTRATE OF CATHEPSIN K FOR IMAGING OSTEOCLAST ACTIVITY AND MIGRATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-01-24 WO disclosed
EP-3344325-A1 LOCAL ADMINISTRATION OF DRUGS FOR THE TREATMENT OF ASTHMA Mercator Medsystems, Inc. (US) 2018-07-11 EP disclosed
EP-3240800-A1 CLOSTRIDIUM DIFFICILE TARGETING MOIETIES AND CONSTRUCTS COMPRISING SAID MOIETIES C3 JIAN, LLC (US) 2017-11-08 EP disclosed
EP-3166959-A1 TARGETING PEPTIDES THAT BIND S. MUTANS, CONSTRUCTS COMPRISING SUCH PEPTIDES AND USES THEREOF C3 Jian, Inc. (US) 2017-05-17 EP disclosed
WO-2017040605-A1 LOCAL ADMINISTRATION OF DRUGS FOR THE TREATMENT OF ASTHMA MERCATOR MEDSYSTEMS, INC. (US) 2017-03-09 WO disclosed
EP-3086646-A2 PLANTS CONTAINING BENEFICIAL ENDOPHYTES Indigo AG, Inc. (US) 2016-11-02 EP disclosed
WO-2016133471-A1 A TOPICAL COMPOSITION COMPRISING MUPIROCIN AND DEXPANTHENOL PHARMACTİVE İLAÇ SANAYİ VE TİCARET A. Ş. (TR) 2016-08-25 WO disclosed
WO-2016109443-A1 CLOSTRIDIUM DIFFICILE TARGETING MOIETIES AND CONSTRUCTS COMPRISING SAID MOIETIES C3 JIAN, INC. (US) 2016-07-07 WO disclosed
WO-2016007551-A1 TARGETING PEPTIDES THAT BIND S. MUTANS, CONSTRUCTS COMPRISING SUCH PEPTIDES AND USES THEREOF C3 JIAN, INC. (US) 2016-01-14 WO disclosed
WO-2015100432-A2 METHOD FOR PROPAGATING MICROORGANISMS WITHIN PLANT BIOREACTORS AND STABLY STORING MICROORGANISMS WITHIN AGRICULTURAL SEEDS SYMBIOTA, INC. (US) 2015-07-02 WO disclosed
WO-2015100431-A2 PLANTS CONTAINING BENEFICIAL ENDOPHYTES SYMBIOTA, INC. (US) 2015-07-02 WO disclosed
EP-2437596-A1 SKIN TREATMENT COMPOSITIONS Ex-Tek, LLC (US) 2012-04-11 EP disclosed
WO-2011084882-A2 METHODS AND COMPOSITIONS FOR ENHANCED IMMUNOLOGICAL THERAPY AND TARGETING OF GRAM-POSITIVE BACTERIA CONTRAFECT CORPORATION (US) 2011-07-14 WO disclosed
WO-2010141711-A1 SKIN TREATMENT COMPOSITIONS EX-TEK, LLC (US) 2010-12-09 WO disclosed