Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | GRB2 | P62993 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106691 | 0.83 | FFAR1 (0.54) | FFAR1PDPK1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL27739671 | 0.73 | TAAR1 (0.46) | SLC1A3SLC1A2SLC1A1FFAR1PDPK1 | |
| SCHEMBL8076087 | 0.72 | FFAR1 (0.50) | FFAR1PDPK1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL27817755 | 0.72 | FFAR1 (0.50) | FFAR1PDPK1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL117230 | 0.71 | FFAR1 (0.73) | FFAR1PDPK1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL16379325 | 0.71 | KCNH2 (0.48) | FFAR1PDPK1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL21553586 | 0.71 | GRM8 (0.55) | FFAR1TAAR1GRB2KIF11 | |
| SCHEMBL22444936 | 0.71 | GRM8 (0.55) | FFAR1TAAR1GRB2KIF11 | |
| SCHEMBL12696328 | 0.70 | TAAR1 (0.52) | FFAR1PDPK1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL2316007 | 0.70 | TAAR1 (0.57) | FFAR1PDPK1PLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082700-A1 | A METHOD FOR THE PREPARATION OF 6,7-DIMETHOXY-1-[2-(4-TRIFLUOROMETHYLPHENYL)ETHYL]-3,4- DIHYDROISOQUINOLINE | ZENTIVA, K.S. (CZ) | 2011-07-14 | — | — | WO | disclosed |