SCHEMBL117230

SCHEMBL117230

O=C(O)CCc1ccc(C(F)(F)F)cc1

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 11/20 0.73
PDPK1 O15530 1/20 0.58
KEAP1 Q14145 1/20 0.57
FFAR4 Q5NUL3 3/20 0.57
PLAAT3 P53816 1/20 0.56
PLAAT5 Q96KN8 1/20 0.56
PLAAT2 Q9NWW9 1/20 0.56
PLAAT4 Q9UL19 1/20 0.56
TAAR1 Q96RJ0 1/20 0.53
PPARA Q07869 1/20 0.52
HDAC1 Q13547 1/20 0.51
HDAC8 Q9BY41 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1454387 0.89 FFAR1 (0.60) FFAR1PDPK1PLAAT3PLAAT5PLAAT2
SCHEMBL30357702 0.88 FFAR1 (0.60) FFAR1PDPK1KEAP1FFAR4PLAAT3
SCHEMBL4037431 0.87 HDAC1 (0.59) FFAR1PDPK1PLAAT3PLAAT5PLAAT2
Hydrochloric Acid SCHEMBL2763476 0.87 FFAR1 (0.59) FFAR1PDPK1PLAAT3PLAAT5PLAAT2
SCHEMBL7332151 0.86 FFAR1 (0.57) FFAR1PDPK1PLAAT3PLAAT5PLAAT2
SCHEMBL23176837 0.85 MAPT (0.62) FFAR1PDPK1PPARAHDAC1HDAC8
SCHEMBL25172817 0.85 MAPT (0.62) FFAR1PDPK1PPARAHDAC1HDAC8
SCHEMBL7090409 0.85 FFAR1 (0.61) FFAR1PDPK1FFAR4PLAAT3PLAAT5
SCHEMBL11801516 0.84 FFAR1 (0.55) FFAR1PDPK1FFAR4PLAAT3PLAAT5
SCHEMBL10681264 0.83 MLYCD (0.60) FFAR1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 487 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-115551846-B 1,4,5, 6-tetrahydropyrimidin-2-amine derivatives UBE株式会社 2024-03-08 CN claimed
CN-114907288-B Application of nitrobenzene compounds in preparation of pseudomonas aeruginosa quorum sensing inhibitor 中国医学科学院医药生物技术研究所 2023-12-08 CN claimed
CN-117143097-A Beta-carbopol compound, preparation method thereof and application of beta-carbopol compound in resisting Alzheimer disease 中国人民解放军北部战区总医院 2023-12-01 CN claimed
WO-2023085396-A1 PHARMACEUTICAL COMPOSITION FOR PROVIDING TREATMENT FOR OR PREVENTING ALPORT SYNDROME UBE株式会社 2023-05-19 WO claimed
CN-115551846-A 1,4,5,6-tetrahydropyrimidin-2-amine derivatives UBE株式会社 2022-12-30 CN claimed
CN-115175907-A Substituted piperazine derivatives useful as T cell activators 百时美施贵宝公司 2022-10-11 CN claimed
CN-110167933-B As αVAzole amides and amines as integrin inhibitors 百时美施贵宝公司 2022-06-21 CN claimed
WO-2017092759-A1 GEPHYRIN BINDING PEPTIDES AND USES THEREOF UNIVERSITY OF COPENHAGEN (DK) 2017-06-08 WO claimed
EP-3433239-B1 SMALL MOLECULE INHIBITORS OF THE NUCLEAR TRANSLOCATION OF ANDROGEN RECEPTOR FOR THE TREATMENT OF CASTRATION-RESISTANT PROSTATE CANCER UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2026-05-27 EP disclosed
US-20260028356-A1 1,3,4,7-TETRAHYDRO-2H-PYRROLO[3',2':5,6]PYRIDO[2,3-B][1,4]OXAZEPINE BCL-2 INHIBITORS ABBVIE INC (US) 2026-01-29 US disclosed
EP-4653451-A1 POLYPEPTIDE COMPOUND AND USE THEREOF Chengdu New Radiomedicine Technology Co., Ltd. (CN) 2025-11-26 EP disclosed
US-20250353863-A1 TRICYCLIC SPIROLACTAM COMPOUNDS WITH ANTIMYCOBACTERIAL ACTIVITY INST NAT SANTE RECH MED (FR) 2025-11-20 US disclosed
WO-2025224599-A1 PYRROLIDINE-BASED GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF PFIZER INC. (US) 2025-10-30 WO disclosed
US-4970328-A MITICIDE, FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 1990-11-13 US disclosed
US-4957533-A THIOAMIDES, AMIDINES ELI LILLY AND COMPANY (US) 1990-09-18 US disclosed
WO-1990006937-A1 DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS ABBOTT LABORATORIES (US) 1990-06-28 WO disclosed
US-4929642-A MITICIDES, FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-05-29 US disclosed
EP-0314422-A2 N-phenylalkylbenzamide fungicides DOWELANCO (US) 1989-05-03 EP disclosed
EP-0300218-A1 Use of substituted 1,4-naphthoquinones against nites and fungi BAYER AG (DE) 1989-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028356-A1 1,3,4,7-TETRAHYDRO-2H-PYRROLO[3',2':5,6]PYRIDO[2,3-B][1,4]OXAZEPINE BCL-2 INHIBITORS BCL9L, BCL2L2, BCL2L1 FFAR1 1483/4885PDPK1 1623/4885KEAP1 2884/4885
US-20250353863-A1 TRICYCLIC SPIROLACTAM COMPOUNDS WITH ANTIMYCOBACTERIAL ACTIVITY TALDO1, TBCA, TBCD FFAR1 3772/4885PDPK1 1248/4885KEAP1 765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.