Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | SCD | O00767 | 5/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPC | P11150 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17775080 | 0.86 | TRPV1 (0.38) | CNR2CNR1SCDDPP4LPL | |
| SCHEMBL19714207 | 0.86 | TRPV1 (0.38) | CNR2CNR1SCDDPP4LPL | |
| SCHEMBL22240211 | 0.85 | ADORA2B (0.34) | CNR2SCDPRMT5WDR77 | |
| SCHEMBL22239940 | 0.83 | GPR6 (0.35) | MEN1KMT2A | |
| SCHEMBL22240203 | 0.80 | SCN9A (0.35) | CNR2SCDLPLLIPCLIPG | |
| SCHEMBL19714097 | 0.80 | CNR2 (0.33) | CNR2CNR1SCDLPLLIPC | |
| SCHEMBL19714287 | 0.80 | CNR2 (0.33) | CNR2CNR1SCDLPLLIPC | |
| SCHEMBL19736388 | 0.79 | TRPV1 (0.38) | CNR2CNR1SCDLPLLIPC | |
| SCHEMBL19714057 | 0.79 | TRPV1 (0.38) | CNR2CNR1SCDLPLLIPC | |
| SCHEMBL22240125 | 0.79 | BTK (0.33) | CNR2CNR1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221317-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-07-22 | — | — | EP | disclosed |