SCHEMBL2223966

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2224730	0.89	GPR6 (0.46)	CYP2C9CYP2D6CYP2C19MEN1CYP1A2
	SCHEMBL12517064	0.87	CCR5 (0.43)	CYP2C9CYP2D6CYP2C19MEN1CYP1A2
	SCHEMBL2224886	0.87	MEN1 (0.50)	CYP2C9CYP2D6CYP2C19MEN1CYP1A2
	SCHEMBL2222942	0.86	GPR6 (0.46)	CYP2C9CYP2D6CYP2C19MEN1CYP1A2
	SCHEMBL2225222	0.86	POLB (0.47)	MEN1KMT2AALDH1A1HSD17B10SMN1; SMN2
	SCHEMBL2223740	0.85	CCR5 (0.47)	CYP2C9CYP2D6CYP2C19MEN1KMT2A
	SCHEMBL2222490	0.85	MEN1 (0.39)	CYP2C9CYP2D6CYP2C19MEN1CYP1A2
	SCHEMBL2222816	0.85	CCR5 (0.46)	CYP2C9CYP2D6CYP2C19MEN1CYP1A2
	SCHEMBL2223112	0.84	KDM4E (0.47)	MEN1KMT2AALDH1A1HSD17B10TSHR
	SCHEMBL14484920	0.83	TNKS (0.44)	CYP2C9CYP2D6CYP2C19MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.