Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 7/20 | 0.33 |
| ▸ | CNR2 | P34972 | 6/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | TEK | Q02763 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19714239 | 1.00 | AXL (0.33) | AXLCNR2CBLBNTRK1MAP4K1 | |
| SCHEMBL19714243 | 1.00 | AXL (0.33) | AXLCNR2CBLBNTRK1MAP4K1 | |
| SCHEMBL19714324 | 0.92 | RPS6KA3 (0.37) | — | |
| SCHEMBL19714533 | 0.92 | NTRK1 (0.37) | AXLCNR2CBLBNTRK1MAP4K1 | |
| SCHEMBL19714017 | 0.92 | RPS6KA3 (0.37) | — | |
| SCHEMBL19714534 | 0.92 | NTRK1 (0.37) | AXLCNR2CBLBNTRK1MAP4K1 | |
| SCHEMBL17777016 | 0.91 | AXL (0.33) | AXLCNR2CBLBNTRK1MAP4K1 | |
| SCHEMBL17770116 | 0.91 | AXL (0.33) | AXLCNR2CBLBNTRK1MAP4K1 | |
| SCHEMBL17769861 | 0.91 | NTRK1 (0.33) | AXLCNR2CBLBNTRK1MAP4K1 | |
| SCHEMBL17770122 | 0.91 | AXL (0.33) | AXLCNR2CBLBNTRK1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221317-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-07-22 | — | — | EP | disclosed |