Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22239716 | 1.00 | KMT2A (0.34) | KMT2AGCKL3MBTL1 | |
| SCHEMBL22240094 | 0.88 | PHGDH (0.36) | KMT2A | |
| SCHEMBL22240292 | 0.88 | MEN1 (0.32) | KMT2A | |
| SCHEMBL22240224 | 0.87 | — | — | |
| SCHEMBL22240024 | 0.87 | ACACB (0.34) | — | |
| SCHEMBL22239948 | 0.85 | — | — | |
| SCHEMBL22240128 | 0.84 | EGFR (0.36) | — | |
| SCHEMBL17769922 | 0.84 | KMT2A (0.37) | KMT2AGCKL3MBTL1 | |
| SCHEMBL17769927 | 0.84 | KMT2A (0.37) | KMT2AGCKL3MBTL1 | |
| SCHEMBL22240191 | 0.83 | KMT2A (0.34) | KMT2AGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221317-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-07-22 | — | — | EP | disclosed |