Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22240057 | 0.91 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL22239724 | 0.90 | TRPV1 (0.31) | TRPV1CNR1CNR2 | |
| SCHEMBL22240094 | 0.89 | PHGDH (0.36) | KMT2APHGDH | |
| SCHEMBL22239716 | 0.88 | KMT2A (0.34) | KMT2A | |
| SCHEMBL22239863 | 0.88 | KMT2A (0.34) | KMT2A | |
| SCHEMBL22240059 | 0.87 | AXL (0.31) | MEN1KMT2AAXL | |
| SCHEMBL22240215 | 0.87 | NOS2 (0.32) | MEN1KMT2A | |
| SCHEMBL22239993 | 0.86 | KDM4E (0.35) | MEN1KMT2A | |
| SCHEMBL22239948 | 0.85 | — | — | |
| SCHEMBL22239757 | 0.84 | MEN1 (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221317-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-07-22 | — | — | EP | disclosed |