Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817919 | 0.87 | LMNA (0.57) | LMNAGAAHPGDMAPTTSHR | |
| SCHEMBL2223461 | 0.87 | LMNA (0.54) | LMNAGAAHPGDTSHRKMT2A | |
| SCHEMBL2222205 | 0.81 | LMNA (0.59) | LMNAGAAHPGDKDM4EHSD17B10 | |
| SCHEMBL2108513 | 0.81 | PPARG (0.46) | LMNAHPGDKDM4EHSD17B10MAPT | |
| SCHEMBL3085601 | 0.79 | LMNA (0.48) | LMNAGAAHPGDTSHRKMT2A | |
| SCHEMBL27787138 | 0.78 | LMNA (0.52) | LMNAGAAHPGDTSHRKMT2A | |
| SCHEMBL19006409 | 0.77 | CYP4F2 (0.45) | LMNAGAAKDM4EHSD17B10MAPT | |
| SCHEMBL2817924 | 0.76 | HDAC1 (0.58) | LMNAGAAHPGDKDM4EMAPT | |
| SCHEMBL5761247 | 0.76 | HDAC1 (0.46) | LMNAGAAHPGDKDM4EHSD17B10 | |
| SCHEMBL3592886 | 0.75 | ESR1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523560-A1 | COMPOUNDS AND METHODS | Tempero Pharmaceuticals, Inc. (US) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011088187-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | disclosed |