⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26085597 | 0.88 | — | — | |
| SCHEMBL855477 | 0.88 | — | — | |
| SCHEMBL10232278 | 0.88 | — | — | |
| SCHEMBL855476 | 0.88 | — | — | |
| SCHEMBL28230079 | 0.88 | — | — | |
| SCHEMBL19662328 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL20983270 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL20983360 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL2730680 | 0.85 | — | — | |
| SCHEMBL24286407 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150473-A2 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | DOGMA THERAPEUTICS, INC. (US) | 2020-07-23 | — | — | WO | disclosed |