⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19662328 | 1.00 | — | — | |
| SCHEMBL855476 | 1.00 | — | — | |
| SCHEMBL10232278 | 1.00 | — | — | |
| SCHEMBL855477 | 1.00 | — | — | |
| SCHEMBL28230079 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL20983360 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL20983270 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2730680 | 0.97 | — | — | |
| SCHEMBL22242701 | 0.88 | — | — | |
| SCHEMBL21974278 | 0.76 | SI (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312490-A1 | MCL-1 INHIBITORS | GILEAD SCIENCES, INC. | 2023-10-05 | — | — | US | disclosed |
| US-11643400-B2 | MCL-1 inhibitors | GILEAD SCIENCES, INC. (US) | 2023-05-09 | — | — | US | disclosed |