SCHEMBL22243991

SCHEMBL22243991

CC1(C)c2cc(-c3cccc(-c4cc(-c5ccccc5)nc(-c5ccccc5)c4)c3)ccc2-c2c1ccc1oc3ccccc3c21

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.35
PLA2G4A P47712 3/20 0.35
PLA2G10 O15496 1/20 0.35
WEE1 P30291 1/20 0.32
ACACA Q13085 2/20 0.32
GAA P10253 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KMT2A Q03164 2/20 0.31
MAPK1 P28482 1/20 0.31
MEN1 O00255 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22243987 0.98 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10WEE1ACACA
SCHEMBL22243815 0.98 WEE1 (0.33) PLA2G2APLA2G4APLA2G10WEE1ACACA
SCHEMBL22243699 0.97 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10WEE1ACACA
SCHEMBL22243705 0.97 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10WEE1ACACA
SCHEMBL22243713 0.95 KMT2A (0.34) PLA2G2APLA2G4AWEE1ACACAGAA
SCHEMBL22243861 0.94 PLA2G2A (0.35) PLA2G2APLA2G4APLA2G10WEE1ACACA
SCHEMBL22243858 0.92 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10WEE1ACACA
SCHEMBL22243988 0.92 MEN1 (0.37) PLA2G2APLA2G4APLA2G10WEE1ACACA
SCHEMBL22243878 0.91 WEE1 (0.33) PLA2G2APLA2G4APLA2G10WEE1ACACA
SCHEMBL22243989 0.90 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10WEE1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200231580-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME DOOSAN CORPORATION (KR) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200231580-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME SLCO4C1, SLCO2A1, POU2F1 PLA2G2A 3976/4885PLA2G4A 4028/4885PLA2G10 4024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.