Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22244946 | 1.00 | HPGD (0.35) | HPGDALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL29760532 | 0.90 | ALDH1A1 (0.33) | HPGDALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL22245089 | 0.90 | ALDH1A1 (0.33) | HPGDALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL22245090 | 0.90 | ALDH1A1 (0.33) | HPGDALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL22232824 | 0.90 | ALDH1A1 (0.33) | HPGDALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL22231470 | 0.88 | ALDH1A1 (0.39) | HPGDALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL22231437 | 0.88 | HPGD (0.43) | HPGDALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL22231433 | 0.88 | HPGD (0.43) | HPGDALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL25097594 | 0.86 | HPGD (0.40) | HPGDALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL25097878 | 0.86 | HPGD (0.40) | HPGDALDH1A1KDM4ECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020148354-A1 | SUBSTITUTED CHROMEN-4-ONE FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2020-07-23 | — | — | WO | disclosed |