Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.35 |
| ▸ | HTR2B | P41595 | 5/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225883 | 0.79 | NOS3 (0.34) | KDM1AKDM1BHTR2CHTR2BNOS3 | |
| SCHEMBL14625429 | 0.77 | HTR2C (0.42) | KDM1AKDM1BHTR2CHTR2BHTR2A | |
| SCHEMBL9787026 | 0.77 | KDM1A (0.41) | KDM1AKDM1BHTR2CHTR2BNOS3 | |
| Hydrochloric Acid SCHEMBL1003456 | 0.76 | KDM1A (0.40) | KDM1AKDM1BHTR2CHTR2BNOS3 | |
| SCHEMBL2792592 | 0.72 | HTR2B (0.39) | HTR2CHTR2B | |
| SCHEMBL10290678 | 0.69 | HTR2B (0.41) | KDM1AKDM1BHTR2CHTR2BHTR2A | |
| SCHEMBL15286446 | 0.69 | HTR2B (0.42) | HTR2CHTR2BHTR2A | |
| SCHEMBL2223694 | 0.69 | KDM1A (0.34) | KDM1AKDM1BNOS3NOS1NOS2 | |
| SCHEMBL25659972 | 0.67 | HTR2C (0.39) | HTR2CNOS3NOS1NOS2HTR2A | |
| SCHEMBL7664077 | 0.65 | RAD52 (0.46) | HTR2CDRD2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | claimed |